Dementia does not necessarily occur genetically, but in some people, it can be more likely due to genetics. The majority of the cases related to dementia, such as those related to Alzheimer’s disease, are as a result of aging, lifestyle habits, vascular conditions, and environmental factors and not as a direct inheritance. Not all early-onset dementia is common; however, there is a possible strong genetic correlation with rare early-onset dementia.
Dementia can be unavoidable, but it does not imply that you will have it because of a family history, as Dr. Gurneet Singh Sawhney, a neurosurgeon in Mumbai, says.
Concerned about memory loss or a family history of dementia? Book an appointment with Dr. Gurneet Singh Sawhney, a leading neurosurgeon in Mumbai, for expert evaluation and guidance.
What is the role of genetics in Dementia?
Dementia can be affected by genetics in two ways.
Risk genes -The risk genes are the ones that predispose the individual to develop dementia but do not cause it directly. Indicatively, there have been cases where individuals have some types of genes that increase their vulnerability. Some people who have such genes, however, do not grow to dementia due to the fact that lifestyle and general health of the brain are also significant factors.
Deterministic genes – These are uncommon genetic mutations, which may directly cause early-onset dementia, typically not after the age of 60. When inherited, they are a major risk factor in the exhibiting of the symptoms at an earlier age.
Besides genetics, there are other risk factors that lead to dementia:
Aging-related changes of the brain – As one ages, natural alterations in the brain structure and functioning may make one vulnerable to cognitive decline.
High blood pressure, diabetes and cholesterol – Lower vascular health may limit blood supply to the brain and may raise the risk of vascular dementia.
Smoking and poor diet – These lifestyles have the potential to hasten the aging of the brain and cause more inflammation.
Past head injuries – Brain trauma may lead to the destruction of nerve cells and increase the risk of dementia in the long run.
Stress and bad sleep – Chronically high stress hormone and sleep deprivation may have an adverse impact on memory and brain regeneration systems.
A thorough neurological examination would help identify the connection between memory issues and hereditary vulnerability or other curable illnesses.
Should you Genetic Testing in case of Dementia in Family?
Genetic testing is not the standard practice with all persons who have relatives with a history of dementia. It is normally taken into account when:
Several of the close relatives ended up having early-onset dementia—this can indicate a more inheritable factor.
Onset of symptoms is anticipated at an early age (before 60 years). – An early onset leads to the suspicion of genetic factors.
Known genetic mutation in the family – In this situation, targeted testing can be used to assist in early planning.
Dr.Gurneet Singh Sawhney , a Neurosurgeon in Mumbai, says.
The tests should never be conducted without adequate counseling because the outcome may bring anxiety without always altering the treatment options.
Why choose Dr. Gurneet Singh Sawhney for dementia evaluation?
Memory changes can be stressful for both patients and families. Dr. Gurneet Singh Sawhney takes a structured and compassionate approach, focusing on accurate neurological assessment rather than assumptions. He combines detailed clinical evaluation with advanced diagnostics when needed, reviews individual risk factors carefully, and creates personalized long-term care plans. His goal is early detection, precise diagnosis, and helping patients maintain cognitive independence while supporting families throughout the journey.
In case of any doubts about change of memory or family background, you can refer to Dr. Gurneet Singh Sawhney, Neurosurgeon in Mumbai, who can provide you with a detailed neurology and specific advice.
FAQ's
Is it always inherited by dementia?
No. Majority does not come directly inheritable, but genetics can be potential risk enhancers.
Will I certainly develop dementia as long as one of my parents did?
Not necessarily. The family history increases the risk but does not ensure development.
What is the typical age of onset of hereditary dementia?
Hereditary early-onset dementia tends to occur in the age before 60 years, although it is rare.
Are lifestyle changes effective in lowering dementia?
Yes. Overall risk can be reduced by control of blood pressure, exercise, healthy diet and mental exercises.
When do I need to see a neurosurgeon when I have memory problems?
In case forgetfulness impairs the everyday functions, gets worse during the course of time, or is accompanied by confusion or changes in personality, medical assessment is recommended.